Assessment
Key takeaways
- Regular check-ins and shared routines helped study participants stick with diet, exercise and brain-healthy activities.
- In-person connections with staff and peers helped participants feel known, supported and accountable.
- Small, visible wins and feedback tools helped participants reshape how they saw their own health.
It’s easy to say we’re going to commit to brain-healthy habits. But after three weeks — or three hours — we’re skipping the gym and vegging out alone on the couch.
So what keeps anyone on track with a good diet, physical and mental exercise, and socializing with pals to support brain health?
For Patty Kelly, it’s her friend Phyllis.
As part of the U.S. POINTER study, Kelly, now 82, had to follow a healthy diet, do brain exercises, socialize with other people and monitor her heart health. The randomized, two-year trial, conducted between 2019 and 2023, included 2,111 adults ages 60 to 79 spread across five sites in the United States. Many, like Kelly, are still being tracked in follow-up.
In 2025, the study’s researchers reported in the medical journal JAMA that the lifestyle changes significantly improved cognition in adults who were at risk of cognitive decline because of family history or health issues. The study was funded by the Alzheimer’s Association.
The regimen was particularly effective for those who got lots of support to adhere to a modified Mediterranean diet known as the MIND diet, complete prescribed brain exercises, and attend monthly meetings with other participants and clinicians. However, even those who were in a self-directed cohort improved and found ways to keep the momentum going during the study’s two years and beyond.
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