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• "Repetitive negative thinking is associated with amyloid, tau, and cognitive decline," Alzheimer's & Dementia, June 2020. This study looked at 292 people over the age of 55 who were part of the Pre-symptomatic Evaluation of Experimental or Novel Treatments for Alzheimer's Disease (PREVENT-AD) cohort and an additional 68 people who were part of the Multi-Modal Neuroimaging in Alzheimer’s Disease (IMAP+) cohort. All participants completed questionnaires about their repetitive negative thinking and moods; some also had brain scans and/or cognitive screening tests done. The researchers found that repetitive negative thinking was associated with cognitive decline. Because this is a population study, it shows a correlation but does not prove cause and effect. Read the full study.
• "Changes in Adult Alcohol Use and Consequences During the COVID-19 Pandemic in the US," JAMA Network Open, September 2020. In this study, researchers surveyed more than 1,500 adults about their alcohol consumption and found that 3 in 4 adults said they were drinking more frequently than they did in 2019. Women in particular also reported more heavy drinking and more alcohol-related problems compared to 2019. Limitations of the study include the fact that it relied on participants’ own reporting of their alcohol consumption. Read the full study.
• "Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study," BMJ, June 2017. In this observation cohort study, 550 men and women with a mean age of 43 reported their alcohol intake weekly and underwent regular cognitive screening tests over the course of 30 years. They also received brain scans. Researchers found that higher alcohol intake was associated with an increased risk of atrophy in the hippocampus. Even moderate drinkers were three times more likely to have hippocampal atrophy. Limitations of the study include the fact that it relied on participants’ own reporting of their alcohol consumption and that, as a population study, it shows a correlation but does not prove cause and effect. Read the full study.
• "Older Adults’ Experience of the COVID-19 Pandemic: A Mixed-Methods Analysis of Stresses and Joys," The Gerontologist, February 2021. Read the full study.
• "Severe Obstructive Sleep Apnea Is Associated with Higher Brain Amyloid Burden: A Preliminary PET Imaging Study," Journal of Alzheimer's Disease, November 2020. Read a summary of the study. (A fee is required to access the full study.)
• "White Matter Integrity in Obstructive Sleep Apnea before and after Treatment," Sleep, September 2014. This study followed 17 people with obstructive sleep apnea for 12 months as they received CPAP treatment. The participants underwent magnetic resonance imaging (MRI) and completed tests to assess their cognitive function. The researchers found that after a year of treatment, the participants had significant improvements in cognitive function as well as an almost complete reversal of white matter abnormalities in the brain. The study was funded by a CPAP manufacturer, and two of the study authors work for a CPAP manufacturer. Read the full study.
• "Sugary beverage intake and preclinical Alzheimer’s disease in the community," Alzheimer's & Dementia, March 2017. In this study of thousands of adults who were part of the Framingham Heart Study, participants filled out questionnaires about what they ate and drank, participated in cognitive testing and received brain MRIs. The researchers found that a higher intake of sugary beverages was associated with lower total brain volume and poorer performance on episodic memory tests. Limitations of the study include the fact that it relied on participants’ own reporting of their sugary beverage consumption and that, as a population study, it shows a correlation but does not prove cause and effect. Read a summary of the study. (A fee is required to access the full study.)
• "Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia," Stroke, April 2017. In this study of more than 4,000 adults who were part of the Framingham Heart Study Offspring cohort, researchers reviewed participants’ food and beverage intake questionnaires and checked for incidents of stroke and dementia. Researchers found an association between artificially sweetened soft drink consumption and an increased risk of stroke and dementia. Limitations of the study include the fact that it relied on participants’ own reporting of their soft drink consumption and that, as a population study, it shows a correlation but does not prove cause and effect. Read the full study.
• "Volunteering Is Associated with Lower Risk of Cognitive Impairment," Journal of the American Geriatrics Society, October 2016. This study looked at 13,262 people over age 60 who were part of the Health and Retirement Study (HRS), in which personal interviews were conducted every two years to assess cognitive function. The researchers found that volunteering later in life is associated with a lower risk of cognitive decline. As a population study, it shows a correlation but does not prove cause and effect. Read the full study.
• "Volunteering and Cardiovascular Disease Risk: Does Helping Others Get ‘Under the Skin?’" The Gerontologist, October 2016. This study looked at data from 7,803 adults who were part of the Health and Retirement Study (HRS). Researchers found that middle-aged volunteers were less likely to have metabolic syndrome as well as risk factors for cardiovascular disease such as elevated blood glucose levels and excess belly fat. As a population study, it shows a correlation but does not prove cause and effect. Read the full study.
• "Volunteer Work and Well-Being," Journal of Health and Social Behavior, June 2001. This study looked at data from 2,681 adults who were part of the Americans’ Changing Lives longitudinal study. Researchers found that volunteering was associated with an improvement in six aspects of personal well-being: happiness, life satisfaction, self-esteem, sense of control over life, physical health and depression. As a population study, it shows a correlation but does not prove cause and effect. Read the full study.
• "Can volunteering in later life reduce the risk of dementia? A 5-year longitudinal study among volunteering and non-volunteering retired seniors," PLoS One, March 2017. Read the full study.
• "Volunteering and Subsequent Health and Well-Being in Older Adults: An Outcome-Wide Longitudinal Approach," American Journal of Preventive Medicine, June 2020. Read a summary of the study. (A fee is required to access the full study.)
• "Ageing attenuates the effect of extracellular hyperosmolality on whole-body heat exchange during exercise-heat stress," The Journal of Physiology, September 2020. In this study of 10 young men (mean age of 25) and 10 middle-aged or older men (mean age of 61) who completed hour-long cycling workouts, researchers found that the older participants weren’t as efficient at regulating changes in body temperature during exercise. Read the full study.
• "Dehydration Impairs Cognitive Performance: A Meta-analysis," Medicine & Science in Sports & Exercise, November 2018. Read the full study.
• "Physical Activity, Cognition, and Brain Outcomes: A Review of the 2018 Physical Activity Guidelines," Medicine & Science in Sports & Exercise, June 2019. This review of research, conducted in part for the 2018 Health and Human Services Physical Activity Guidelines for Americans Advisory Committee, looked at systematic reviews, meta-analyses and pooled analyses. Researchers found an association between moderate- to vigorous-intensity physical activity and better cognitive function. Read the full study.
• "Lifestyle Risk Factors and Cognitive Outcomes from the Multidomain Dementia Risk Reduction Randomized Controlled Trial, Body Brain Life for Cognitive Decline (BBL-CD)," Journal of the American Geriatrics Society, November 2020. Read a summary of the study. (A fee is required to access the full study.)
• "Impact of smoking on cognitive decline in early old age: the Whitehall II cohort study," Archives of General Psychiatry, June 2012. Read the full study.
• "Effect of smoking cessation on the risk of dementia: a longitudinal study," Annals of Clinical and Translational Neurology, September 2018. Read the full study.
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