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How Much Do You Know About Menopause and the Brain?

Test your knowledge on how these changes during midlife affect a woman’s mood and brain


A woman in a cozy orange sweater gazes thoughtfully out of a window, resting her chin on her hand
Stefania Pelfini la Waziya/Getty Images

This quiz was written with the help of AI. It was reviewed by human editors and fact-checked before publishing.

Question 1 of 10

What hormonal change influences brain function during menopause?

The main hormonal shift in menopause is a significant drop in estrogen levels. This decline is linked to the memory and concentration issues many women refer to as “brain fog.”

Question 2 of 10

During which phase of menopause is brain fog most likely to occur?

Perimenopause, which can last from four to eight years, is the transitional phase before menopause when estrogen levels drop and menstrual cycles become irregular. About 60 percent of women have memory, focus and attention problems during this phase, studies show.

Question 3 of 10

What percentage of women say that brain fog is their most troublesome menopause symptom at work?

In a 2023 national survey by the Society for Women’s Health Research, 78 percent of participants said brain fog was the most bothersome menopause symptom at work. Other common symptoms included sleep problems (79%), weight gain (68%) and mood shifts (66%).

Question 4 of 10

How are perimenopause-related mood symptoms different from PMS?

Symptoms of PMS, or premenstrual syndrome, come on in the week or so before a woman’s regular period. Perimenopause mood issues, on the other hand, can come and go without any pattern or trigger.

Question 5 of 10

Mood changes during menopause can result from:

Changing hormones are not the only issues women are facing in midlife. Disrupted sleep and general life stressors, such as family and work responsibilities, can all cause mood shifts during menopause.

Question 6 of 10

Which group is at increased risk of mood issues during perimenopause?

Women who had hormone-related mood changes, like PMS or postpartum depression, earlier in life are at increased risk of mood issues during perimenopause. Talk to your doctor to find out if you’ve started perimenopause and to discuss treatments.

Question 7 of 10

Brain fog during menopause is a sign of which of the following:

Brain fog during menopause is a result of decreasing levels of the hormone estrogen. It is not dementia or cognitive decline, and it doesn’t mean that you will get dementia or Alzheimer's later in life.

Question 8 of 10

What does recent research say about menopausal hormone therapy?

While earlier studies suggested that menopausal hormone therapy (MHT) carried health risks, newer research shows MHT’s benefits, such as fewer mood swings and hot flashes. Benefits generally outweigh risks for women under 60 or who are within 10 years of starting menopause. MHT is not usually recommended for women with a history of breast or endometrial cancer, stroke, heart attack, blood clots or liver disease. 

Question 9 of 10

True or false: Menopause-related brain issues are permanent for women who do not use hormone therapy.

While brain changes during menopause may seem scary, memory and attention issues are usually temporary and improve after menopause, even without hormone therapy.

Question 10 of 10

Which of the following can help with mood shifts during menopause?

Antidepressants, hormone therapy and cognitive behavioral therapy may all be helpful for mood swings during menopause. For minor mood shifts, lifestyle changes —such as good sleep hygiene; exercise; and a healthy diet, like the Mediterranean diet — can help. 

You have unanswered questions. Please go back and complete those questions to finish the quiz.

Learn more about women, brain health and menopause here.

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